6,6′-Methylene-bis[(3RS)-9-methyl-3-[(2-methyl-1H-imidazol-1-yl)methyl]-1,2,3,9-tetrahydro-4H-carbazol-4-one - Names and Identifiers
Name | 6,6'-Methylenebis[(3RS)-9-methyl-3-[(2-methyl-1H-imidazol-1-yl)methyl]-1,2,3,9-tetrahydro-4H-carbazol-4-one]
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Synonyms | ONDANSETRON DIMER Ondansetron Impurity B Ondansetron HCl EP IMpurity-B Ondansetron Hydrochloride Dihydrate EP Impurity B 6,6'-Methylenebis[1,2,3,9-tetrahydro-9-Methyl-3-[(2-Methyl-1H-iMidazol-1-yl)Methyl]-4H-carbazol-4-one 6,6'-Methylenebis[(3RS)-9-methyl-3-[(2-methyl-1H-imidazol-1-yl)methyl]-1,2,3,9-tetrahydro-4H-carbazol-4-one] 6,6′-Methylene-bis[(3RS)-9-methyl-3-[(2-methyl-1H-imidazol-1-yl)methyl]-1,2,3,9-tetrahydro-4H-carbazol-4-one 6,6'-Methylenebis[(3RS)-9-Methyl-3-[(2-Methyl-1H-iMidazol-1-yl)Methyl]-1,2,3,9-tetrahydro-4H-carbazol-4-one
(Ondansetron IMpurity B) 6,6'-Methylenebis[(2RS)-9-methyl-3-[(2-methyl-1H-imidazol-1-yl)methyl]-1,2,3,9-tetrahydro-4H-carbazol-4-one)(Ondansetron Impurity B) 9-methyl-3-[(2-methylimidazol-1-yl)methyl]-6-[[9-methyl-6-[(2-methylimidazol-1-yl)methyl]-5-oxo-7,8-dihydro-6H-carbazol-3-yl]methyl]-2,3-dihydro-1H-carbazol-4-one
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CAS | 1076198-52-1
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6,6′-Methylene-bis[(3RS)-9-methyl-3-[(2-methyl-1H-imidazol-1-yl)methyl]-1,2,3,9-tetrahydro-4H-carbazol-4-one - Physico-chemical Properties
Molecular Formula | C37H38N6O2
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Molar Mass | 598.74 |
Density | 1.35±0.1 g/cm3(Predicted) |
Melting Point | >240?C (dec.) |
Boling Point | 896.5±60.0 °C(Predicted) |
Solubility | Chloroform (Slightly), DMSO (Very Slightly), Methanol (Slightly, Heated) |
Appearance | Solid |
Color | White to Pale Beige |
pKa | 7.80±0.33(Predicted) |
Storage Condition | -20°C Freezer |
6,6′-Methylene-bis[(3RS)-9-methyl-3-[(2-methyl-1H-imidazol-1-yl)methyl]-1,2,3,9-tetrahydro-4H-carbazol-4-one - Introduction
Ondansetron hydrochloride impurity B(EP) is a chemical substance whose chemical name is 6,6 '-methylene BIS [(3RS)-9-Methyl -3-[(2-methyl -1H imidazol-1-yl) methyl]-1,2,3, 9-tetrahydro-4H-carbazol-4-one]. The following is a description of the properties, uses, preparation and safety information of ondansetron:
Nature:
-Ondansetron Impurity B(EP) is a white or off-white crystalline solid.
-It is soluble in water and organic solvents such as methanol and ethanol at room temperature.
-The chemical structure of ondansetron hydrochloride impurity B(EP) makes it biologically active.
Use:
-Ondansetron hydrochloride impurity B(EP) is one of the impurities of ondansetron, which can be used as a reference substance in drug research and production.
-It can be used for the quality control and analysis of ondansetron pharmaceutical preparations.
Preparation Method:
-The preparation method of ondansetron hydrochloride impurity B(EP) includes synthesis from the corresponding raw material compound through chemical reaction.
Safety Information:
-Ondansetron hydrochloride impurity B(EP) has limited safety information and should be used in accordance with reasonable laboratory practices.
-Follow chemical safety procedures during use and avoid contact with skin, eyes and mucous membranes.
-In case of accidental contact or inhalation, wash immediately or obtain medical assistance.
-When handling and storing ondansetron hydrochloride impurity B(EP), the corresponding safe operation guidelines and regulatory requirements should be followed.
Last Update:2024-04-09 02:00:54